Flexible and reliable neuromodulation with simultaneous EEG

Any combination of electrodes can be used for EEG recording or as sources or sinks for

• transcranial direct current stimulation (tDCS)
• transcranial alternating current stimulation (tACS)
• pulsed direct current stimulation (tPCS)

Record EEG concurrently with neuromodulation to evaluate neuromodulatory effects on brain activity.

Proprietary software and hardware for precise cortical targeting

• Planning based on the reciprocity principle quickly calculates ideal electrode configuration to modulate the cortical target
• 3D images show predicted negative and positive cortical radial current density distributions so you can
  evaluate and modify the plan
• EGI’s AccuCharge Circuit continually balances source channels with sink channels to maintain the desired current levels over time
• Protocols can be created with varying durations, waveforms, frequencies, and pulse durations
• Includes ability to design sham protocols

Realistic head models for better accuracy
EGI’s high­ resolution FDM head models are accurate for describing the underlying geometry of the conductive tissues, and also for how current flows through the head volume to the scalp.

• Uses 7 different tissue types — scalp, skull, cerebrospinal fluid, grey matter, white matter, air, and eyeballs
• Uses 3D sensor positions to define the path of electrical current from the cortex to the scalp
• The FDM calculates electric potentials voxel­ by ­voxel from 1 mm MRI images

Integration with GeoSource 3 Research electrical source imaging software to define target selection

• Choice of individual head models, atlas head models or conformal/warped atlas head models from MRI data
• Use source estimation to identify functionally significant positive and negative cortical regions that be used as targets for neuromodulation

Designed with important safety features
Multiple software and hardware controls limit current levels to less than 200 μAmps per electrode or 1 mAmp total.

The GTEN 100 Research Neuromodulation System is available as a beta release. 

GTEN 100 Research neuromodulation system is available as a conversion package to EGI’s Geodesic EEG System (GES) 400.

The complete integrated system requires purchase of:

1. GTEN 100 Research Conversion Package — 32, 64, 128, or 256 channel (Beta Release)

• Net Amps 400 amplifier conversion to Net Amps GTEN 100 amplifier
• GTEN targeting and planning software module
• GTEN control software module
• 2 Day On-Site Training Visit

2. Geodesic EEG System 400*

3. 256-channel HydroCel Geodesic Sensor Net (GSN) 130 — sponged or LTM

4. GeoSource 3 Research — Basic, Intermediate, OR Advanced Package

• Basic includes GeoSource 3 software and 1 mm resolution FDM atlas head models
• Intermediate adds the ability to include individual sensor positions to create 1 mm resolution FDM conformal atlas head models
• Advanced adds the ability to import MRI data to create 1 mm resolution FDM individual head models

5. Geodesic Photogrammetry System or GeoScan Sensor Digitization Device
For registration of individual sensors to the head model, used in creating a conformal atlas (in GeoSource 3 Research Intermediate) or individual head model (in GeoSource 3 Research Advanced).

NOTE: Once the Net Amps 400 amplifier in your GES 400 system is converted to a GTEN 100 amplifier, it will still record EEG signals, but will no longer be a clinically cleared device and will be FOR RESEARCH USE ONLY.

See the talk titles and e-posters presented by EGI scientists and collaborators at the 2017 Brain Stimulation and Imaging Meeting and the Organization for Human Brain Mapping 2017 Annual Meeting.

View EGI's GTEN Symposium presented at OHBM 2016. See it now with EGI SYMPOSIA OnDemand.

Learn about the science behind GeoSource 3 source imaging and GTEN 100 Neuromodulation

EGI's study using GTEN 100 Research System and pulsed protocols showed long-term depression of motor cortex excitability, sustained over 90 minutes following current injection. Read the paper.