Dense Array EEG Neuroimaging

Patient friendly procedure

Not only has dEEG been shown to yield clinically important information, it is also most cost effective and can be used with a broader range of patients, compared to other methods. Dense array EEG can be used at the bedside, is tolerant of patient movement during the procedure, and requires no radiation or dedicated procedure room. EGI's dEEG system is especially patient friendly, requiring no scalp abrasion, glues, restraints, or sedation.

A valuable tool in presurgical planning

For patients suffering from focal epilepsy that cannot be controlled by medication, surgery to resect the epileptic zone can offer relief from symptoms, resulting in a higher quality of life. A comprehensive presurgical evaluation is critical to a positive surgical outcome.

Dense array EEG (dEEG) with 128 or 256 electrodes is attracting interest as an important tool for use in epilepsy presurgical planning. Recent large-scale studies indicate that dEEG compares favorably to other noninvasive methods, such as conventional EEG, PET (positron emission tomography), ictal SPECT (single-photon emission computed tomography), and MRI (magnetic resonance imaging), for identifying the irritative zone in focal epilepsy (see for example Brodbeck et al (2011). Used with specialized software, such as GeoSource 2.0, dEEG data can be used for visualization of human brain function.

Research studies

The October 2011 issue of Brain contains the first large-scale study of the relative contribution of 128- and 256-channel dense array EEG (dEEG) to the presurgical planning process. Drawing on their decade of experience with dEEG, the groups lead by Dr. Seeck and Dr. Michel reported that dEEG supports both review of seizure data acquired in an extended monitoring setting and their innovative interictal spike protocol methods.

Recent references on electrical source imaging with dense array EEG

Malpass, K. (2011) Epilepsy: Electric source imaging—an inexpensive and reliable method to estimate the epileptic focus. Nature Reviews Neurology 7, 658. doi:10.1038/nrneurol.2011.186

Brodbeck, V., Spinelli, L., Lascano, A., Wissmeier, M., Vargas, M., Vulliemoz, S., Pollo, C., Schaller, K., Michel, C., and Seeck, M.l (2011). Electroencephalographic source imaging: a prospective study of 152 operated epileptic patients. Brain 134 (10), 2887-2897. doi:10.1093/brain/awr243.

Recommended Products

128-, 256-Channel Clinical GES 300 Routine Package

GeoSource software

Geodesic Photogrammetry System (GPS)

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